Molecular mechanisms and functional consequences of P2X7 purinoceptor activation

Prof. Dr. Friedrich Nolte (AG Molekulare Immunologie)

The goal of the project is to elucidate the molecular mechanisms and functional consequences of P2X7 purinoceptor activation by ATP vs. ADP-ribosylation using site directed mutagenesis and transgenic mouse models.

Laufzeit: 2009-2011
Förderung: DFG (Teilprojekt PAK 362: Purinnukleotide und T-Zellregulation)